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. 2017 Feb 22;17:151. doi: 10.1186/s12885-017-3137-4

Table 3.

Post-ABSCT treatment, toxicities and supportive care

Parameters Overall cohort Outpatient treatment Hospital admission P-value
ABSCT number, n 21 14 7 /
Treatment duration
 Overall, days 21 (18–31) 21 (18–25) 22 (19–31) 0.38
 Days as outpatient 19 (8–25) 21 (18–25) 15 (8–19) <0.01
 Days as inpatient 0 (0–18) / 5 (2–18) <0.01
Reason for hospital admission, n (%) /
 Neutropenic fever ≥72 h 4 (19) / 4 (57)
 Grade III stomatitis 2 (10) / 2 (29)
 Other 1 (5) / 1 (14)
Toxicities
 Stomatitis, n (%)
  I 17 (81) 13 (93) 4 (57)
  II 2 (10) 1 (7) 1 (14)
  III 2 (10) 0 (0) 2 (29)
 Neutropenic fever
  n, (%) 14 (67) 8 (57) 6 (86) 0.34
  No. of days with fever 3 (1–10) 2 (1–7) 4 (2–10) 0.14
 Diarrhoea, n (%) 1 (5) 1 (7) 0 (0) 1.00
 Pulmonary infection, n (%) 0 (0) 0 (0) 0 (0) 1.00
 Urinary tract infection, n (%) 1 (5) 0 (0) 1 (14) 0.33
 Positive blood cultures, n (%)
  Peripheral 4 (19) 1 (7) 3 (43) 0.09
  Central 0 (0) 0 (0) 0 (0) 1.00
 Port catheter infection, n (%)
  Suspicion of 3 (14) 0 (0) 3 (43) 0.03
  Proven 0 (0) 0 (0) 0 (0) 1.00
  Port catheter explantation 3 (14) 0 (0) 3 (43) 0.03
 SAE, n (%) 0 (0) 0 (0) 0 (0) 1.00
Support/Intervention
 Red cell transfusion, n (%) 6 (29) 3 (21) 3 (43) 0.35
 Platelet transfusion, n (%) 15 (71) 9 (64) 6 (86) 0.61
 i.v. antibiotics
  In case of neutropenic fever, n (%) 14 (67) 8 (57) 6 (86) 0.34
  At subfebrile temperature, n (%) 5 (24) 4 (29) 1 (14) 0.62
  Overall, days 7 (4–14) 7 (4–10) 8 (4–14) 0.61
  Days as outpatient 6 (1–10) 7 (4–10) 1 (0–6) /
  Days as inpatient 5 (2–14) / 5 (2–14) /

ABSCT autologous blood stem cell transplantation, i.v. intravenous, no. number, SAE severe adverse event. Unless otherwise indicated, data are given as medians (range)