Table 4.
Association between AMY1A copy number and obesity risk
| Study | Obese cases | Controls | OR (95% CI)b | P value | ||
|---|---|---|---|---|---|---|
| n | AMY1A copiesa | n | AMY1A copiesa | |||
| Adults | 1179 | 6.8 ± 2.5 | 2220 | 7.0 ± 2.6 | 0.98 (0.95–1.01) | 0.13 |
| Children/Adolescents | 785 | 7.0 ± 2.6 | 712 | 7.3 ± 2.7 | 0.94 (0.90–0.98) | 7.1 × 10−3 |
| Combined analysis | – | – | – | – | 0.97 (0.94–0.99) | 6.8 × 10−3 |
aData are means ± standard deviation
bOdds ratio per AMY1A copy from a logistic regression adjusted for age and sex
AMY1A salivary amylase gene, CI confidence interval, OR odds ratio