Table 3.
Comparison of laboratory data, at hospital admission, between survivors and non-survivors patients with visceral leishmaniasis
| Non-survivors (N = 34) | Survivors (N = 251) | p | |
|---|---|---|---|
| Hemoglobin (g/dL) | 6.5 ± 1.8 | 7.5 ± 1.5 | < 0.001 |
| Hematocrit (%) | 20.4 ± 5.0 | 23.1 ± 4.6 | 0.002 |
| Leukocytes (/mm3) | 3904 (900–16,800) | 3688 (300–11,000) | 0.01 |
| Platelets (103/mm3) | 32.0 ± 28.6 | 84.0 ± 62.1 | 0.017 |
| Urea (mg/dL) | 57.1 ± 37.9 | 51.8 ± 38.9 | 0.469 |
| Creatinine (mg/dL) | 1.07 ± 0.47 | 1.15 ± 1.13 | 0.750 |
| Sodium (mEq/L) | 130.6 ± 5.4 | 133.2 ± 4.2 | 0.005 |
| Potassium (mEq/L) | 4.2 ± 0.8 | 4.0 ± 0.6 | 0.297 |
| Albumin (g/dL) | 2.04 ± 0.74 | 2.70 ± 0.79 | < 0.001 |
| Globulins (g/dL) | 4.26 ± 1.26 | 4.32 ± 1.65 | 0.915 |
| AST (U/L) | 295 (12–2161) | 104 (13–1165) | 0.039 |
| ALT (U/L) | 192 (5–1071) | 78 (4–603) | 0.065 |
| Total bilirubin (mg/dL) | 7.0 (1.0–22.3) | 1.3 (0.04–21.1) | < 0.001 |
| Direct Bilirubin (mg/dL) | 5.4 (0.66–17.79) | 0.9 (0.07–16.7) | < 0.001 |
| Indirect Bilirubin (mg/dL) | 1.6 (0.08–7.0) | 0.4 (0.06–4.4) | 0.04 |
| Arterial pH | 7.34 ± 0.14 | 7.44 ± 0.06 | 0.059 |
| HCO3 (mEq/L) | 16.7 ± 7.1 | 20.7 ± 6.5 | 0.178 |
| PCO2 (mmHg) | 36.7 ± 10.1 | 31.6 ± 6.2 | 0.044 |
AST aspartate aminotransferase, ALT alanine aminotransferase, HCO3 serum bicarbonate, PCO2 carbon dioxide partial pressure
Values were represented as mean ± SD or median (range). Student’s T test and Mann-Whitney tests were used. P ≤ 0.05 was considered statistically significant