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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Clin Immunol. 2016 Sep 12;173:87–95. doi: 10.1016/j.clim.2016.09.006

Figure 3. Post-vaccination increases in multifunctional (MF) CD4+T EM cells.

Figure 3

S. Typhi (A), S. Paratyphi A (B) and S. Paratyphi B (C) -infected target specific CD4+ TEM MF cells were subdivided into 11 different subsets based on the possible combinations of simultaneous production IFN-γ, TNF-α and/or IL-2- and/or expression of CD107a using the FCOM analysis tool. Shown are the post-vaccination peak increases in the 5/11 dominant subsets and sum of the remaining 6/11 (Others) subsets of specific MF cells. Data are presented as mean percentages of total MF cells for each subset and “Others” in Ty21a vaccinees (n=16).

Post vaccination increase: Peak level at days 42 or 84 post-vaccination minus the corresponding pre-vaccination levels. No statistical significant differences were observed among the various subsets with one way ANOVA (non parametric).