Figure 7. Concomitant expression of the gut homing molecule integrin α4β7 by MF cells.
PBMC collected from Ty21a vaccinees (n=12) were stimulated with S. Typhi-, S. Paratyphi A-, and S. Paratyphi B-infected targets and the sum of all CD4+ T EM MF subsets that co-expressed integrin α4β7 (α4β7+) or not (α4β7-) were calculated using the FCOM analysis tool.
Horizontal bars represents mean±SEM of the post-vaccination increases calculated as peak responses at days 42 or 84 minus pre-vaccination [day 0] levels.
*p<0.05, # p=0.06, Wilcoxon signed rank test, 2-tail.