Table 6.

Comparison of OPTN class 5 and LI-RADS category 5

Size	OPTN classification	LI-RADS category
1–2 cm HCC	OPTN class 5A: ≥1 cm, <2 cm measured in late arterial or portal venous phase images. Increased arterial enhancement during the late hepatic arterial phase and washout during the later phases of contrast enhancement and peripheral rim enhancement (capsule or pseudocapsule). OPTN class 5A-g: increased contrast enhancement in the late hepatic arterial phase and growth by ≥50% documented on serial CT or MR images obtained ≤6 months apart.	LR-5: 10–19 mm mass with arterial-phase hyperenhancement and ≥2 of the following: washout appearance, capsule appearance, or threshold growth.
≥2 cm HCC	OPTN class B: increased contrast enhancement in late hepatic arterial phase and either washout during later contrast phases or peripheral rim enhancement (capsule or pseudocapsule).	LR-5: ≥20 mm mass with arterial-phase hyperenhancement and ≥1 of the following: washout appearance, capsule appearance, or threshold growth.
HCC with tumor in vein	Imaging not provided as patients with tumor in vein are not eligible for liver transplant.	LR-5V: HCC with tumor in vein; definite enhancing tissue in vein.

Notes: See Table 2 for LI-RADS classification and Table 5 for OPTN classification system for nodules seen on images of cirrhotic livers. Data from OPTN/UNOS Liver and Intestinal Organ Transplantation Committee. Report to the Board of Directors; 2016. Available from: http://optn.transplant.hrsa.gov37 and Wald et al.²³

Abbreviations: LI-RADS, Liver Imaging Reporting and Data System; HCC, hepatocellular carcinoma; CT, computed tomography; MR, magnetic resonance; OPTN, Organ Procurement and Transplantation Network.