Table 2. Comparison of C5aR1 expression in different myeloid cells in response to OVA treatment.
MFI BAL | MFI Lung | MFI mLN | p value MFI between compartments | |
---|---|---|---|---|
Eosinophils | 1168 ± 152aa | 634 ± 85 | - | <0.01 |
Neutrophils | 4381 ± 381 | 3796 ± 485 | - | 0.35 |
Macrophages | 6895 ± 424bbb | 2355 ± 423 | - | <0.001 |
CD11b+ cDC | - | 155 ± 30§§§ | 132 ± 41 | 0.64 |
moDC | - | 1835 ± 280 | 666 ± 207 | <0.01 |
Shown are normalized GFP MFI values (mean ± SEM);
a,b depict significant differences between the MFIs of aBAL-derived eosinophils vs neutrophils, beosinophils vs macrophages respectively, in the OVA treated group.
§ depicts significant differences between MFIs of lung CD11b+ cDCs vs. moDCs in the OVA treatment group.
aa p<0.01; and
§§§,bbb p<0.001.