Fig 2. Patterns of genomic aberrations highlighted by high-resolution aCGH in CRC.

a) Shows pattern 1 from 3 patients as examples (upper 22 autosomes). The zoomed inset focused on an area of chromosome arm 3P with 2 small deletions. b) Shows 4 cases of CRC with pattern 2. Notice the large number of small aberrations that alternate between gain-baseline-loss. Insets show zoomed in picture of chromosome 7 from one patients (upper panels) and chromosome 1 from a different case. Notice how well-demarcated and clear are these alternating aberrations. c) Shows a case with pattern 3, which involves copy number alterations of chromosomal arms or whole chromosomes (Insets). In all figures deletions are shown in red and deviate below the 0 (log2 ratio) and gains are depicted in blue.