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. Author manuscript; available in PMC: 2017 Feb 23.
Published in final edited form as: J Sleep Med Disord. 2016 Aug 25;3(6):1064.

Table 2.

OSA and increased comorbidities worldwide.

OSA Associated Comorbidities Study Designed N Study Title Future Intervention Ref
Positive Depression Stepwise linear regression analysis. 1,327 Prevalence and Predisposing Factors for Depressive Status in Chinese Patients with Obstructive Sleep Apnea: A Large- Sample Survey. CPAP (Dai et al, 2016)
Positive COPD Cross-sectional 404 Predictive Factors Warrant Screening for Obstructive Sleep Apnea in COPD: a Taiwan National Survey CPAP (Hang et al, 2016)
Positive Type 2 D.M HTN Ischemic Hrt Diseases Stroke Arrhythmias Depression Cross-sectional 1,704,905 The Effect of Sex and Age on the Comorbidity Burden of OSA: An Observational Analysis from a Large Nationwide US Health Claims Database. CPAP (Mokhlesi et al, 2016)
Positive HTN (39%) Obesity (34%) Depression (19%) GERD (18%) DM (15%) Hypercholesterolemia (10%) Asthma (4%) Retrospective 100 Comorbidities Associated with Obstructive Sleep Apnea: A Retrospective Study CPAP (Pinto et al, 2016)
Positive Nocturnal Heart block Cross-sectional 72 Screening and Managing Obstructive Sleep Apnea in Nocturnal Heart Block Patients: An Observational Study CPAP WU et al, 2016)