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. 2016 Aug 22;7(40):64631–64648. doi: 10.18632/oncotarget.11502

Table 1. Clinical ophthalmic observation and analysis for the subretinal transplantation of PDMS and PDMS-PmL bioscaffold at post-implantation 6, 12, and 24 months.

Group Post-implantation month Cornea/Lens by Slit-Lamp examination IOP (mmHg) by Pneumotonogram Vitreous Media by Color fundi photography Implant/Retina features by Color fundi photography Implant/Retina features by OCT examination
PDMS (n=4) 6 Normal 15.2 ± 2.1 Clear Implant in situ Retina well-looking Implant stable Photoreceptor layer mild edema
12 Normal 14.3 ± 2.3 Clear Implant in situ Retina whitening/atrophy Implant stable Photoreceptor/RPE layer partial degenerated
24 Normal 15.6 ± 1.5 Clear Implant in situ Retina atrophy Implant stable Photoreceptor/RPE layer partial loss
PDMS-PmL (n=6) 6 Normal 15.1 ± 1.7 Clear Implant in situ Retina well-looking Implant stable Photoreceptor/RPE layer intact
12 Normal 15.7 ± 1.9 Clear Implant in situ Retina well-looking Implant stable Photoreceptor/RPE layer intact
24 Normal 15.3 ± 1.8 Clear Implant in situ Retina well-looking Implant stable Photoreceptor/RPE layer intact

PDMS (n = 4 pigs); PDMS-PmL (n = 6 pigs)