Table 2. Comparison of p53 immunohistochemistry data with sex distribution and mean age of patients with TP53 somatic mutations based on the IARC TP53 Database (R17).
| p53 IHC | Male | Female | p-value | |
|---|---|---|---|---|
| Mean age at diagnosis (SD) | negative | 58.567 (± 15.062) | 55.896 (± 15.391) | 0.0182a |
| positive | 57.220 (± 15.772) | 56.439 (±16.860) | 0.2646a | |
| p53 IHC (%) | negative | 496 (23.65%) | 691 (24.71%) | 0.8851b |
| positive | 1601 (76.35%) | 2106 (75.29%) |
(IHC=immunohistochemistry; SD=Standard deviation;
a
Mann-Witney U-test;
b
Pearson's chi square test; Significant p-values are marked in bold)