Table 1. Associations between CXCL1 expression and clinicopathologic variables of HCC patients n (%).
Clinical characteristic | CXCL1 | P-value | ||
---|---|---|---|---|
All cases (n= 119) | High expression | Low expression | ||
Gender(Female/Male) | 0.712 | |||
Female | 19 | 13 (16.9) | 6 (14.3) | |
Male | 100 | 64 (83.1) | 36 (85.7) | |
Cirrhosis | 0.156 | |||
No | 18 | 9 (11.7) | 9 (21.4) | |
Yes | 101 | 68 (88.3) | 33 (78.6) | |
AFP (≥ 400/< 400) | 0.024 | |||
≥ 400 ng/mL | 35 | 28 (36.4) | 7 (16.7) | |
< 400 ng/mL | 84 | 49 (63.6) | 35 (83.3) | |
HBV-DNA (Positive/Negative) | 0.982 | |||
Positive (≥ 5.0 × 102) | 65 | 35 (45.5) | 19 (45.2) | |
Negative (< 5.0 × 102) | 54 | 42 (54.5) | 23 (54.8) | |
Microvascular invasion (Yes/No) | 0.321 | |||
Yes | 32 | 23 (29.9) | 9 (21.4) | |
No | 87 | 54 (70.1) | 33 (78.6) | |
TNM stage (I/II/III) | 0.099 | |||
I | 67 | 38 (49.4) | 29 (69.0) | |
II | 28 | 20 (26.0) | 8 (19.0) | |
III | 24 | 19 (24.7) | 5 (11.9) | |
Differentiation (Poorly/Moderately - Well) | 0.001 | |||
Poorly | 33 | 25 (32.5) | 2 (4.8) | |
Moderately - Well | 86 | 52 (67.5) | 40 (95.2) | |
Tumor size (≥ 5 cm/< 5 cm) | 0.683 | |||
≥ 5 cm | 65 | 36 (46.8) | 18 (42.9) | |
< 5 cm | 54 | 41 (53.2) | 24 (57.1) |