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. 2016 Aug 17;7(40):65052–65066. doi: 10.18632/oncotarget.11350

Table 1. Associations between CXCL1 expression and clinicopathologic variables of HCC patients n (%).

Clinical characteristic CXCL1 P-value
All cases (n= 119) High expression Low expression
Gender(Female/Male) 0.712
Female 19 13 (16.9) 6 (14.3)
Male 100 64 (83.1) 36 (85.7)
Cirrhosis 0.156
No 18 9 (11.7) 9 (21.4)
Yes 101 68 (88.3) 33 (78.6)
AFP (≥ 400/< 400) 0.024
≥ 400 ng/mL 35 28 (36.4) 7 (16.7)
< 400 ng/mL 84 49 (63.6) 35 (83.3)
HBV-DNA (Positive/Negative) 0.982
Positive (≥ 5.0 × 102) 65 35 (45.5) 19 (45.2)
Negative (< 5.0 × 102) 54 42 (54.5) 23 (54.8)
Microvascular invasion (Yes/No) 0.321
Yes 32 23 (29.9) 9 (21.4)
No 87 54 (70.1) 33 (78.6)
TNM stage (I/II/III) 0.099
I 67 38 (49.4) 29 (69.0)
II 28 20 (26.0) 8 (19.0)
III 24 19 (24.7) 5 (11.9)
Differentiation (Poorly/Moderately - Well) 0.001
Poorly 33 25 (32.5) 2 (4.8)
Moderately - Well 86 52 (67.5) 40 (95.2)
Tumor size (≥ 5 cm/< 5 cm) 0.683
≥ 5 cm 65 36 (46.8) 18 (42.9)
< 5 cm 54 41 (53.2) 24 (57.1)