Table 2. Genes differentially expressed in hIMB cells 24 h after DUX4-plasmid transfection.
DUX4 24 h | ||||
---|---|---|---|---|
FC | Gene | Description | ref | |
501.4 | RFPL2 | ret finger protein-like 2 | ‡ | |
200.5 | ZSCAN4 | zinc finger and SCAN domain containing 4 | ‡ | |
184.3 | TRIM64 | tripartite motif containing 64 | ‡ | |
166.0 | USP29 | ubiquitin specific peptidase 29 | ‡ | |
140.0 | TRIM43 | tripartite motif containing 43 | ‡ | |
121.1 | RFPL3 | ret finger protein-like 3 | ‡ | |
109.1 | PRAMEF2 | PRAME family member 2 | ‡ | |
69.3 | ZIM3 | zinc finger. imprinted 3 | ||
63.9 | TRIM49 | tripartite motif containing 49 | ‡ | |
60.2 | RFPL1 | ret finger protein-like 1 | ‡ | |
56.1 | PRAMEF1 | PRAME family member 1 | ‡ | |
42.3 | SLC34A2 | solute carrier family 34 (type II sodium/phosphate contransporter). member 2 | ‡ | |
38.4 | LEUTX | leucine twenty homeobox | ||
38.0 | MRAP2 | melanocortin 2 receptor accessory protein 2 | ||
36.3 | RFPL4B | ret finger protein-like 4B | ‡ | |
* | 32.8 | HPX-2 | homeobox HPX-2 | |
26.2 | MBD3L2 | methyl-CpG binding domain protein 3-like 2 | ‡ | |
24.4 | PRAMEF9. PRAMEF25. PRAMEF19. PRAMEF22 | PRAME family member 9;PRAME family member 25;PRAME family member 19;PRAME family member 22 | ‡ | |
19.8 | TRIM48 | tripartite motif containing 48 | ‡ | |
19.7 | KHDC1 | KH homology domain containing 1 | ‡ | |
18.0 | PRAMEF8 | PRAME family member 8 | ‡ | |
17.2 | CCDC30 | coiled-coil domain containing 30 | ||
13.6 | DKK2 | dickkopf WNT signaling pathway inhibitor 2 | ||
13.3 | CLDN14 | claudin 14 | ||
13.1 | TRIM51. TRIM51HP | tripartite motif-containing 51;tripartite motif-containing 51H. pseudogene | ||
11.8 | FAM90A1 | family with sequence similarity 90. member A1 | ‡ | |
* | 10.9 | DUX3 | double homeobox 3 | |
10.24 | FRG2 | FSHD region gene 2 | ||
8.61 | CCNA1 | cyclin A1 | ||
8.14 | PNP | purine nucleoside phosphorylase | ||
7.75 | SNAI1 | snail family zinc finger 1 | ||
7.34 | HIST1H3H | histone cluster 1. H3h | ||
6.19 | NT5C1B | 5′-nucleotidase. cytosolic IB | ||
6.17 | SRSF8 | serine/arginine-rich splicing factor 8 | ||
5.69 | DHRS2 | dehydrogenase/reductase (SDR family) member 2 | ||
5.33 | RBBP6 | retinoblastoma binding protein 6 | ||
4.96 | MYB | v-myb avian myeloblastosis viral oncogene homolog | ||
4.92 | SNX22 | sorting nexin 22 | ||
4.79 | FOXP2 | forkhead box P2 | ||
4.78 | DGKE | diacylglycerol kinase. epsilon 64kDa | ||
4.37 | CHML | choroideremia-like (Rab escort protein 2) | ||
4.32 | HBEGF | heparin-binding EGF-like growth factor | ||
4.14 | KCNAB2 | potassium voltage-gated channel. shaker-related subfamily. beta member 2 | ||
4.10 | SPINK1 | serine peptidase inhibitor. Kazal type 1 | ||
3.84 | PLA2G5 | phospholipase A2. group V | ||
3.30 | FLRT3 | fibronectin leucine rich transmembrane protein 3 | ||
3.22 | HIST1H3F | histone cluster 1. H3f | ||
3.20 | ESM1 | endothelial cell-specific molecule 1 | ||
3.17 | GRAMD1C | GRAM domain containing 1C | ||
3.01 | SIAH1 | siah E3 ubiquitin protein ligase 1 | ‡ | |
... | ... | ... | ||
–3.19 | JAKMIP3 | Janus kinase and microtubule interacting protein 3 | ||
* | –3.36 | HCAR2 | hydroxycarboxylic acid receptor 2 | |
–3.51 | LMO7DN | LMO7 downstream neighbor | ||
–4.10 | RBBP8NL | RBBP8 N-terminal like | ||
–7.00 | GFRA2 | GDNF family receptor alpha 2 | ||
–8.72 | CACNA1F | calcium channel. voltage-dependent. L type. alpha 1F subunit |
Asterisk labels genes that are also differentially expressed in DUX4c-transfected IMBs.