Table 3. Genes differentially expressed in hIMB cells 12 h after DUX4c-plasmid transfection.
| DUX4c 12 h | |||
|---|---|---|---|
| FC | Gene | Description | |
| * | 19.1 | HPX-2 | homeobox HPX-2 |
| * | 13.2 | DUX3 | double homeobox 3 |
| * | 4.1 | SERPINA3 | serpin peptidase inhibitor. clade A (alpha-1 antiproteinase. antitrypsin). member 3 |
| * | 3.8 | ABCA1 | ATP-binding cassette. sub-family A (ABC1). member 1 |
| * | 3.4 | CCL20 | chemokine (C-C motif) ligand 20 |
| * | 3.0 | GCG | glucagon |
| * | 3.0 | CXCL3 | chemokine (C-X-C motif) ligand 3 |
| * | 2.7 | CXCL2 | chemokine (C-X-C motif) ligand 2 |
| * | 2.7 | TNFAIP2 | tumor necrosis factor. alpha-induced protein 2 |
| * | 2.7 | APOC1 | apolipoprotein C-I |
| * | 2.6 | APOE | apolipoprotein E |
| * | 2.6 | MFSD2A | major facilitator superfamily domain containing 2A |
| 2.5 | CLSTN2 | calsyntenin 2 | |
| * | 2.5 | HEATR9 | HEAT repeat containing 9 |
| * | 2.5 | EFNA1 | ephrin-A1 |
| * | 2.5 | CCL2 | chemokine (C-C motif) ligand 2 |
| * | 2.5 | CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity. alpha) |
| * | 2.5 | TNFAIP6 | tumor necrosis factor. alpha-induced protein 6 |
| * | 2.5 | NFIL3 | nuclear factor. interleukin 3 regulated |
| * | 2.5 | PTX3 | pentraxin 3. long |
| * | 2.4 | FOXO1 | forkhead box O1 |
| * | 2.4 | KLF15 | Kruppel-like factor 15 |
| * | 2.4 | FOS | FBJ murine osteosarcoma viral oncogene homolog |
| * | 2.3 | NR4A3 | nuclear receptor subfamily 4. group A. member 3 |
| * | 2.3 | CHI3L2 | chitinase 3-like 2 |
| * | 2.3 | MTSS1 | metastasis suppressor 1 |
| * | 2.3 | DEFB119 | defensin. beta 119 |
| * | 2.3 | CFHR4 | complement factor H-related 4 |
| * | 2.3 | PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| * | 2.2 | CSF3 | colony stimulating factor 3 (granulocyte) |
| * | 2.2 | CYTIP | cytohesin 1 interacting protein |
| * | 2.2 | BCL7A | B-cell CLL/lymphoma 7A |
| 2.2 | CFI | complement factor I | |
| * | 2.2 | CYP21A2 | cytochrome P450. family 21. subfamily A. polypeptide 2 |
| * | 2.2 | ZC3H12A | zinc finger CCCH-type containing 12A |
| * | 2.1 | CXCL8 | chemokine (C-X-C motif) ligand 8 |
| * | 2.1 | PDE4DIP | phosphodiesterase 4D interacting protein |
| * | 2.1 | CFB | complement factor B |
| * | 2.1 | HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| * | 2.1 | WISP1 | WNT1 inducible signaling pathway protein 1 |
| * | 2.1 | EGR1 | early growth response 1 |
| * | 2.1 | YAP1 | Yes-associated protein 1 |
| 2.1 | AOC3 | amine oxidase. copper containing 3 | |
| * | 2.1 | TNFAIP3 | tumor necrosis factor. alpha-induced protein 3 |
| * | 2.1 | ENDOV | endonuclease V |
| * | 2.0 | PIM3 | Pim-3 proto-oncogene. serine/threonine kinase |
| * | 2.0 | NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor. epsilon |
| * | 2.0 | IPCEF1; CNKSR3 | interaction protein for cytohesin exchange factors 1; CNKSR family member 3 |
| * | 2.0 | LSMEM1 | leucine-rich single-pass membrane protein 1 |
| * | 2.0 | TMEM165 | transmembrane protein 165 |
| 2.0 | COLEC12 | collectin sub-family member 12 | |
| ... | ... | ... | |
| – 2.1 | HIP1 | huntingtin interacting protein 1 | |
| – 2.1 | SAPCD2 | suppressor APC domain containing 2 | |
| – 2.1 | CDCA7 | cell division cycle associated 7 | |
| * | – 2.2 | PRPH2 | peripherin 2 (retinal degeneration. slow) |
| – 2.2 | AGMAT | agmatine ureohydrolase (agmatinase) | |
| – 2.2 | KRTAP1-5 | keratin associated protein 1-5 | |
| * | – 2.3 | HMGA2 | high mobility group AT-hook 2 |
| – 2.3 | PAQR5 | progestin and adipoQ receptor family member V | |
| – 2.3 | MCM4 | minichromosome maintenance complex component 4 | |
| – 2.4 | CDC6 | cell division cycle 6 | |
| – 2.6 | SSTR1 | somatostatin receptor 1 | |
Asterisk labels genes that are also differentially expressed in DUX4-transfected IMBs.