Figure 3. GATA3 knockdown in T lymphoma cell lines leads to the decreased expression of T_H2-associated cytokines.

(A) After GATA3 shRNA lentiviral transfection, GATA3 mRNA expression was decreased in Hut78 cells. (B) After GATA3 shRNA lentiviral transfection, GATA3 protein expression was decreased in Hut78 cells. (C) GATA3 knockdown in Hut78 cells led to decreased expression of IL-4, IL-5, IL-13, and VEGFA.