Table 2. The MIC and FICI values determined for 3BP and BSO (used solely or in combination) in the case of tested Cryptococcus neoformans cells*.
Compounds | MIC# alone | MIC combined | FICI## |
---|---|---|---|
3BP | 0.15 − 0.2 | 0.03 − 0.04 | 0.33 − 0.38 [S] |
BSO | 60 − 80 | 8 − 10 |
MIC - Minimal Inhibitory Concentration given at mM of active compound;
FICI – Fractional Inhibitory Concentration Indices;
Tests performed on modified minimal synthetic medium (SD) with glucose replaced by sucrose (2%), pH 5.5. Five clinical Cryptococcus neoformans strains were included in this study.