Table 2. Blood brain barrier permeability of HL156A.
Compound | Time | Plasma(ng/mL) | Brain(ng/g) | BP ratio (Cbrain/Cplasma) |
---|---|---|---|---|
HL156A | 0.5 | 582.67 | 99.2 | 0.17 |
3 | 172.33 | 63.07 | 0.37 | |
Metformin | 0.5 | 583.5 | 74 | 0.13 |
3 | 534.33 | 50.13 | 0.1 |
Compound | Time | Plasma(ng/mL) | Brain(ng/g) | BP ratio (Cbrain/Cplasma) |
---|---|---|---|---|
HL156A | 0.5 | 582.67 | 99.2 | 0.17 |
3 | 172.33 | 63.07 | 0.37 | |
Metformin | 0.5 | 583.5 | 74 | 0.13 |
3 | 534.33 | 50.13 | 0.1 |