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. 2016 Sep 1;7(40):66003–66019. doi: 10.18632/oncotarget.11788

Figure 1. CKI inhibits proliferation and induces apoptosis of MCF-7 cells.

Figure 1

A. Inhibition of MCF-7 cell proliferation with CKI treatment. The level of viability of cells under different treatments was measured using XTT:PMS. Data are represented as mean ±SEM (n=6). B. and C. Induction of apoptosis in MCF-7 cells with CKI treatment. The level of apoptosis was determined by measuring the levels of Annexin V and PI staining: B) Percentages of Annexin V+/PI+ cells, and C) representative plots of Annexin V and PI staining. Data are represented as mean ±SEM (n=6). Statistical analyses were performed using A) two-way ANOVA or B) t-test comparing with “untreated” (*p<0.05, **p<0.01, ****p<0.0001).