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. 2016 Sep 1;7(40):66032–66050. doi: 10.18632/oncotarget.11797

Figure 12. Rig-G downregulates MiR21/PTEN and miR181b-1/CYLD pathways through STAT3.

Figure 12

A and B. MiR181b-1 and miR21 expression levels were analyzed in A549 sublines pTRE and Tet-On Rig-G respectively transfected with indicated expression plasmids (A) or shRNA plasmids (B). The cells were cultured in the presence of Dox (2 μg/mL). The results are expressed as the mean ± SEM (n = 5), ***p < 0.001. (B) A549 sublines pTRE and Tet-On Rig-G respectively transfected with indicated expression plasmids C. or shRNA plasmids D. were analyzed for the expression of the indicated proteins by immunoblot analysis.