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. 2016 Sep 1;7(40):66032–66050. doi: 10.18632/oncotarget.11797

Figure 4. Rig-G protein results in decreased tumor growth in vivo.

Figure 4

A. Nude mice were injected subcutaneously with the indicated cell lines, and the expression of Rig-G was examined by immunohistochemistry of paraffin-embedded sections. Scale bars = 100 μm. B. Tumors overexpressing Rig-G showed significantly slower growth (n = 5). C. Percentage of Ki-67-positive tumor cells. The results are expressed as the mean ± SEM, (n = 5), ***p< 0.001. D. Paraffin-embedded tumor sections were analyzed after staining with an anti-Ki-67 antibody. Scale bars = 100 μm. E. Apoptotic cells were identified by TUNEL staining. Scale bars = 100 μm.