Table 3. Allele frequencies in cases and controls and odds ratio estimates for TB.
SNP ID | Gene | Position | Alleles Aa/B | p value | MAF | HWE p | ORs(95%CI) | p value | |
---|---|---|---|---|---|---|---|---|---|
case | control | ||||||||
rs6436917 | SP110 | 231038160 | G/A | 0.0221* | 0.514 | 0.445 | 1.0000 | 1.32 (1.04,1.67) | 0.0221* |
rs4327230 | SP110 | 231046783 | G/C | 0.0001* | 0.078 | 0.188 | 0.7379 | 0.37 (0.25,0.55) | 0.0001* |
rs2114591 | SP110 | 231050569 | C/T | 0.0002 * | 0.203 | 0.302 | 0.3317 | 0.59 (0.45,0.78) | 0.0002 * |
rs7580912 | SP110 | 231081405 | C/T | 0.7104 | 0.399 | 0.388 | 0.5182 | 1.05 (0.82,0.14) | 0.7104 |
rs13422 | PMP22 | 15134175 | A/C | 0.0025* | 0.447 | 0.358 | 0.4358 | 1.45 (1.14,1.84) | 0.0025* |
rs230915 | PMP22 | 15148256 | G/A | 0.2531 | 0.268 | 0.299 | 0.8060 | 0.86 (0.66,1.12) | 0.2531 |
rs231024 | PMP22 | 15157972 | A/G | 0.0700 | 0.281 | 0.332 | 0.4193 | 0.79 (0.61,1.02) | 0.0700 |
MAF, minor allelic frequency; HWE, Hardy-Weinberg Equilibrium; ORs, odds ratios; CI: confidence interval.
Minor allele; *p≤0.05.
Bonferroni's multiple adjustment was applied, with p<0.00178 (0.05/28).