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. 2016 Aug 31;7(40):66149–66159. doi: 10.18632/oncotarget.11710

Table 2. Features of nodules in different calcification groups.

Features Non-calcification group* (n=177) Micro-calcification group* (n=159) Macro-calcification group * (n=181) P value @
No. of males/females 34/143 39/120 38/143 0.488
Age # 49.8 ± 13.6 [18-80] 52.5 ± 13.3 [23-82] 52.4 ± 12.0 [23-78] 0.134
No. of nodules 177 159 181 <0.001
No. of benign nodules 140 (79.1) 94 (59.1) 112 (61.9)
No. of malignant nodules 37 (20.9) 65 (40.9) 69 (38.1)
Size (mm) # 20.3 ± 10.9 [10.0-62.6] 19.6 ± 8.7 [10.0-59.7] 20.3 ± 8.0 [12.3-53.3] 0.748
Conventional SE score 0.041
No. of score 1 1 (0.6) 0 (0) 0 (0)
No. of score 2 41 (23.2) 31 (19.4) 40 (22.1)
No. of score 3 93 (52.5) 64 (40.3) 73 (40.3)
No. of score 4 35 (19.7) 48 (30.2) 54 (29.8)
No. of score 5 7 (4.0) 16 (10.1) 14 (7.7)
ARFI SE grade 0.012
No. of grade 1 1 (0.6) 1 (0.6) 0 ()
No. of grade 2 41 (23.2) 21 (13.2) 34 (18.0)
No. of grade 3 89 (50.3) 63 (39.6) 83 (45.9)
No. of grade 4 34 (19.2) 41 (25.8) 41 (22.7)
No. of grade 5 10 (5.6) 30 (18.9) 22 (12.2)
No. of grade 6 2 (1.1) 3 (1.9) 1 (0.6)
Maximum SWS of nodule # (m/s) 3.31 ± 2.01 [0.56-8.40] 4.64 ± 2.64 [0.70-8.40] 4.79 ± 2.67 [0.54-8.40] < 0.001
Mean SWS of nodule # (m/s) 2.60 ± 1.49 [0.43-8.21] 3.27 ± 1.85 [0.85-8.01] 3.68 ± 2.26 [0.41-8.32] < 0.001
Maximum SWS of surrounding tissue # (m/s) 2.55 ± 0.78 [0.91-5.88] 2.60 ± 0.69 [1.26-7.88] 2.65 ± 0.91 [0.82-7.64] 0.466
Mean SWS of surrounding tissue # (m/s) 2.21 ± 0.72 [0.80-5.88] 2.37 ± 0.78 [1.10-6.24] 2.27 ± 0.80 [0.42-6.35] 0.142
*

Numbers in parentheses are percentages.

#

Data are means ± standard deviations. Ranges are in brackets.

@

P values of nonparametric variables were determined by Chi-square test, and P values of continuous variables by one way analysis of variation.

Abbreviation: SE, strain elastography; ARFI, acoustic radiation force impulse; SWS, shear-wave speed.