Figure 3. Proposed mechanism of CBFβ-SMMHC inhibitors.

Schematic representation of proposed CBFβ-SMMHC activities A. in the absence of inhibitors, or in the presence of B. Ro5-3335, C. AI-10-49, or D. 22d. Proteins are represented by the colored shapes labeled in (A). Ac: Acetylation group.