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. 2016 Aug 26;7(40):66310–66322. doi: 10.18632/oncotarget.11624

Figure 1. Schematic representation of the IκB family of proteins.

Figure 1

Figure 1

A. The cytoplasmic IκB proteins. Notes: PEST: domain rich in proline, glutamic acid, serine and threonine; AR: ankyrin-repeat; NES: nuclear export signal; NIS: nuclear import signal; RHD: Rel homology domain; GRR: glycine-rich region. b. The nuclear IκB proteins. Notes: AR: ankyrin-repeat; NLS: nuclear localization signal; TAD: transactivating domain.