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. Author manuscript; available in PMC: 2017 Aug 13.
Published in final edited form as: Nature. 2017 Feb 13;542(7642):475–478. doi: 10.1038/nature21355

Extended Data Figure 6. Methylation profiles of Ythdf2 target transcripts.

Extended Data Figure 6

a, Examples of Ythdf2 RNA targets harboring both m6A-seq peaks and m6A-CLIP-seq peaks. Coverage of m6A immunoprecipitation (IP) and input fragments are indicated in red and blue, respectively. m6A-CLIP-seq peaks are highlighted in green. Grey lines signify CDS borders.

b, The dynamics of m6A immunoprecipitation (IP) signals over time in Ythdf2 RNA targets. Coverage of m6A immunoprecipitation (IP) and input fragments are indicated in red and grey, respectively. The locations of consensus motifs of GGACU and AGACU are indicated as blue dots. Red lines show splice junctions. Blue squares mark the peaks identified from the m6A-seq signals. Example genes shown: buc, mtus1a, mylipa, setdb1a, tdrd1, vps26a, and zgc:162879.