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. Author manuscript; available in PMC: 2018 Mar 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2016 Dec 29;37(3):466–475. doi: 10.1161/ATVBAHA.116.308749

Table 1.

Plasma variables during indicated weeks on HFHS diet

Measurements Genotype Weeks on a diet
4 8 12 16 24
Insulin
(ng/mL)		 Control 1.47
± 0.16 		7.33
± 3.23 		12.48
± 4.07		 11.01
± 2.76		 12.30
± 2.99
NOX4−/− 1.06
± 0.21 		2.76
± 2.76 		9.67
± 4.45		 9.46
± 3.54		 11.68
± 3.78
GTT insuin
(ng/mL)		 Control 2.81
± 0.70		 6.41
± 3.53		 8.81
± 2.42 		11.01
± 2.23 		11.19
± 1.92
NOX4−/− 1.97
± 0.53		 4.16
± 3.13		 4.22
± 1.41 		6.42
± 1.99 		9.43
± 3.37
Adiponectin
(µg/mL)		 Control 24.59
± 3.22		 24.99
± 1.54		 15.06
± 1.00 		15.57
± 2.45 		16.79
± 4.15
NOX4−/− 24.18
± 2.74		 25.52
± 6.06		 21.53
± 2.65 		20.65
± 2.74 		16.84
± 2.62
SAA
(µg/mL)		 Control 3.78
± 1.62		 5.86
± 1.95		 39.98
± 14.18		 59.58
± 41.14		 35.23
± 7.53
NOX4−/− 4.50
± 2.14		 12.18
± 6.55		 36.23
± 51.87		 44.86
± 33.86		 43.21
± 13.94
Triglycerides
(mg/dL)		 Control 67.98
± 8.25 		94.16
± 21.98 		57.14
± 7.61 		63.60
± 14.39 		63.17
± 12.54
NOX4−/− 36.43
± 11.77 		39.17
± 11.58 		40.69
± 14.18 		43.22
± 4.40 		45.17
± 10.67
Cholesterol
(mg/dL)		 Control 155.26
± 11.44		 173.54
± 13.21		 272.28
± 36.19 		266.68
± 12.36 		287.20
± 37.72
NOX4−/− 111.52
± 43.27		 144.96
± 44.26		 190.62
± 47.31 		206.84
± 54.93 		206.09
± 46.67

Vales represent mean ± SD (n=4–6 per group). Bold font P< 0.05 vs control mice on indicated weeks on a diet.