Table 1.

Effect of different formulations of BoNT on CD.

Question	Answer	Level of recommendation
Is abobotulinumtoxinA effective in improving CD?	Yes	A
Is incobotulinumtoxinA effective in improving CD?	Yes	B
Is onabotulinumtoxinA effective in improving CD?	Yes	A
Is rimabotulinumtoxinA effective in improving CD?	Yes	A
Does BoNT-A treatment improve quality of life?	Yes	B
Does BoNT-A reduce pain associated with CD?	Yes	A
Do BoNT-A and BoNT-B have a comparable effect and duration of effect on dystonia?	Yes	A
Do BoNT-A and BoNT-B have the same rate of side effects?	No (side effects are more frequent with BoNT-B)	B
What is the conversion ratio of onabotulinumtoxinA to abobotulinumtoxinA?	1 IU to 3 IU 1 IU to 2.5 IU	A B
What is the conversion ratio of onabotulinumtoxinA to incobotulinumtoxinA?	1 IU to 1 IU	B

BoNT, botulinum neurotoxin; CD, cervical dystonia.