Fig. 6.

Fundus photographs (left column), indocyanine green angiography images (ICGA, middle column), and optical coherence tomography (OCT) images (right column) obtained from a 63-year-old man with polypoidal choroidal vasculopathy (PCV) treated with fixed-dosing aflibercept. a, b At baseline, exudative changes related to PCV are apparent with branching vascular network (BVN) and polypoidal vessels noted on ICGA images (arrows). c, d Although polyps present at baseline completely regressed after three monthly injections, BVN growth and new polyp formation occurred at 3 months (arrows). e, f New polyps and BVN growth were still present at 12 months (arrows on ICGA image). g–l Study OCT images shown that the macula remained dry from 3 to 12 months