Table 2.
Symbola | Descriptionb | GenBank accession no. | GenBank/NCBI reference sequence | UniProtKB/Swiss-Prot Gene Ontology | UniProtKB accession no. | ||
---|---|---|---|---|---|---|---|
function | Process | Component | |||||
Differentially expressed genes | |||||||
polk | DNA polymerase kappa | FM009023 | KKF10166 | DNA binding, DNA-directed DNA polymerase activity, transferase activity | DNA repair, translesion synthesis, nucleotide-excision repair, DNA gap filling | Nucleus, nucleoplasm | Q9UBT6 |
rnf213 | E3 ubiquitin-protein ligase RNF213 | FM016314 | XP_008298790 | Ubiquitin-protein transferase activity, protein binding | Protein ubiquitination | Cytoplasm, nucleolus, membrane | Q63HN8 |
rab2a | Ras-related protein Rab-2A | FM000715 | XP_008332898 | GTPase activity, protein binding, GTP binding | Mitotic cell cycle, intracellular protein transport, metabolic process | Nucleus, Golgi membrane, endoplasmic reticulum, membrane | P61019 |
kctd12 | BTB/POZ domain-containing protein KCTD12 | FM024677 | XP_008308481 | Poly(A) RNA binding | Regulation of G protein-coupled receptor protein signaling pathway, protein homooligomerization | Plasma membrane, presynaptic membrane, synapse | Q96CX2 |
gba | Glucosylceramidase | FM021788 | XP_010748685 | Glucosylceramidase activity, receptor binding, hydrolase activity | Response to hormones (testosterone, estrogen, glucocorticoid) and pH, metabolic process (lipid, carbohydrate, sphingolipid, glycosphingolipid) | Lysosome membrane, lysosome lumen | P04062 |
plec(2) | Plectin-like isoform X5 | FM008272 | XP_011603659 | Protein binding, poly(A) RNA binding | Cellular component disassembly involved in execution phase of apoptosis, programmed cell death, apoptotic process | Cytoplasm, plasma membrane | Q15149 |
plec(1) | Plectin-like isoform X3 | FM004961 | XP_010767028 | Protein binding, poly(A) RNA binding | Cellular component disassembly involved in execution phase of apoptosis, programmed cell death, apoptotic process | Cytoplasm, plasma membrane | Q15149 |
usp5(1)
usp5(2) usp5(3) |
Ubiquitin carboxyl-terminal hydrolase 5 | FM016194 | XP_010733307 | Ubiquitin-specific protease activity, protein binding, metal ion binding, hydrolase activity, cysteine-type peptidase activity | Ubiquitin-dependent protein catabolic process, positive regulation of proteasomal ubiquitin-dependent protein catabolic process, protein K48-linked deubiquitination | Lysosome | P45974 |
cenpf(1)
cenpf(2) cenpf(3) |
Centromere protein F (No. 1) | FM016762 | XP_010730622 | Protein binding, protein homodimerization activity, transcription factor binding | Regulation of G2/M transition of mitotic cell cycle, chromosome segregation, metaphase plate congression, kinetochore assembly, regulation of striated muscle tissue development | Chromosome centromeric region, kinetochore, nucleus, cytosol | P49454 |
mem-prot | – | FM024907 | WP_038038408 | n/a | n/a | n/a | n/a |
hy-prot(3) | – | FM013574 | WP_033116978 | n/a | n/a | n/a | n/a |
hy-prot(1) | – | FM005046 | WP_030404274 | n/a | n/a | n/a | n/a |
tsfm | TSFM Ts translation elongation factor, mitochondrial | FM024343 | KKF32528 | Translation elongation factor activity | Translational elongation | Mitochondrion | B5X5B4 |
irf7 | Interferon regulatory factor 7 | FM005989 | KKF30244 | Protein binding, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity | Regulation of adaptive immune response, regulation of transcription, DNA-templated, regulation of innate immune response | Nucleus, cytoplasm | P70434 |
gcn1l1(1)
gcn1l1(2) |
Translational activator GCN1 (No. 1) | FM024347 | KKF24933 | Translation factor activity, RNA binding | Regulation of translation | Cytoplasm, ribosome, membrane | Q92616 |
fucolectin | Fucolectin-4 | FM025664 | KKF16053 | Fucose binding, carbohydrate binding, calcium ion binding, metal ion binding | Regulation of complement activation, lectin pathway, regulation of cellular defense response, regulation of innate immune response | Extracellular region | Q9I928 |
alg5 | Dolichyl-phosphate beta-glucosyltransferase | FM024334 | KKF15163 | Transferase activity, transferring glycosyl groups | Protein glycosylation, post-translational protein modification, transferase activity | Endoplasmic reticulum, endoplasmic reticulum membrane | Q9Y673 |
n-f(4) | – | FM024309 | – | – | – | – | – |
n-f(5) | – | FM027632 | – | – | – | – | – |
n-f(6) | – | FM028757 | – | – | – | – | – |
n-f(7) | – | FM019745 | – | – | – | – | – |
n-f(8) | – | FM015144 | – | – | – | – | – |
n-f(9) | – | FM021366 | – | – | – | – | – |
n-f(10) | – | AM984356 | – | – | – | – | – |
n-f(11) | – | FM021366 | – | – | – | – | – |
n-f(12) | – | FM007989 | – | – | – | – | – |
n-f(13) | – | FM000334 | – | – | – | – | – |
n-f(14) | – | FM002847 | – | – | – | – | – |
n-f(15) | – | FM010821 | – | – | – | – | – |
n-f(16) | – | FM001796 | – | – | – | – | – |
n-f(17) | – | FM014863 | – | – | – | – | – |
n-f(18) | – | FM014863 | – | – | – | – | – |
n-f(19) | – | FM020519 | – | – | – | – | – |
n-f(20) | – | FM014863 | – | – | – | – | – |
Genes exhibiting the most stable expression level | |||||||
hspa14 | Heat shock 70 kDa protein 14 | FM023807 | KKF23225 | Protein and ATP binding | “De novo” cotranslational protein folding | Cytoplasm, cytosol, membrane, ribosome | Q0VDF9 |
cops3 | COP9 signalosome complex subunit 3 | FM027858 | XP_008300965 | Protein binding | Ubiquitin-dependent protein catabolic process, in utero embryonic development, signal transduction, protein binding | Nucleus, cytoplasm | Q9UNS2 |
mtif3 | Translation initiation factor IF-3, mitochondrial | FM022743 | KKF15983 | Translation initiation factor activity | Mitochondrial translational initiation | Mitochondrion | Q9H2K0 |
eif3ea | Eukaryotic translation initiation factor 3 subunit E-A | FM026913 | KKF20815 | Translation initiation factor activity | Regulation of translational initiation | Nucleus, cytoplasm | Q6DRI1 |
hectd3 | E3 ubiquitin-protein ligase HECTD3 | FM020929 | KKF23624 | Ubiquitin-protein transferase activity | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | Cytoplasm | Q3U487 |
eif3e | Eukaryotic translation initiation factor 3 subunit E | FP237239 | XP_010738667 | Translation initiation factor activity, protein binding | Regulation of translational initiation | Nucleus, cytoplasm, cytosol | P60228 |
Numbers in parenthesis represent number of subsequent gene, when more than one gene with the same name was identified
Specific, not described symbols: n-f protein was not found, hy-prot only sequence of hypothetical protein could be found, mem-prot refer to unspecified membrane protein, un prot only sequence for uncharacterized protein was found
aFor all the genes, when possible, gene symbol identical to human one was given
bFor all the genes, when possible, gene description identical to human one was given