Effect of orthovanadate (OV) on genistein in human atrial myocytes. (A) Time course of I
Kur recorded with the voltage protocol as shown in the inset in a typical experiment in the absence and presence of 30 μM daidzein or 30 μM genistein. I
Kur traces at corresponding time points are shown in right side of the panel. (B) Time course of I
Kur recorded in an atrial myocyte in the absence and presence of 30 μM genistein, and genistein plus 1 mM OV. I
Kur traces at corresponding time points are shown in right side of the panel. (C) Histogram showing the mean percent values of I
Kur during control, in the presence of 30 μM daidzein (n = 5), 30 μM genistein, genistein plus 1 mM OV (n = 7). *P < 0.05, significantly different from control; #P < 0.05, significantly different from genistein alone or 1 mM OV alone (n = 5).