Table 2.

Genes and SNPs in telomere‐maintenance genes associated with overall survival of ovarian cancer

Gene	Chr	SNP	Genotype	Position	dbSNP	MAF		Model*	HR† (95% CI)	P‐value	Q‐value
					Func annot	Case	Control
TEP1	14	rs10143407	C>G	20831794	3′UTR	0.494	0.516	DOM	2.01 (1.21–3.32)	0.007	0.076
TEP1	14	rs1713423	T>C	20860073	Intron	0.083	0.089	ADD	0.53 (0.34–0.85)	0.008	0.076
TEP1	14	rs2151753	G>A	20880328	Intron	0.158	0.135	DOM	1.57 (1.09–2.26)	0.015	0.076
TEP1	14	rs938887	A>G	20847202	Asp5230/synonymous	0.215	0.185	ADD	2.39 (1.22–4.66)	0.011	0.076
TNKS	8	rs10093972	T>C	9451369	Intronic	0.046	0.068	DOM	1.88 (1.20–2.92)	0.006	0.076
TNKS	8	rs33944167	G>A	9564485	Pro1439/synonymous	0.069	0.072	DOM	1.81 (1.13–2.91)	0.014	0.076
TNKS	8	rs6990116	T>C	9577096	Intron	0.074	0.083	DOM	1.83 (1.15–2.92)	0.011	0.076

*Models of inheritance: Add‐additive; Dom‐dominant; Rec‐recessive. ^†Adjusted for age, histology, clinical stage, tumour grade and treatment.