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. 2017 Jan 19;6(3):288–294. doi: 10.1016/j.molmet.2017.01.006

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© 2017 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Body weight, locomotor activity, energy expenditure, and fat oxidation of Lep^ob/+/GIP^+/+, Lep^ob/ob/GIP^+/+, and Lep^ob/ob/GIP^gfp/gfp male mice. (A) Body weight tracking of Lep^ob/+/GIP^+/+ (white circles), Lep^ob/ob/GIP^+/+ (gray circles), and Lep^ob/ob/GIP^gfp/gfp mice (black circles) in cohort 1 (n = 5–8) and cohort 2 (n = 4–6). (B) Locomotor activity, energy expenditure and fat oxidation of Lep^ob/+/GIP^+/+ (white bars), Lep^ob/ob/GIP^+/+ (gray bars), and Lep^ob/ob/GIP^gfp/gfp mice (black bars) at 34–35 weeks of age in cohort 2 (n = 3–6). *P < 0.05, **P < 0.01, ***P < 0.001 compared to Lep^ob/ob/GIP^+/+. n.s; not significantly different. Data are mean ± SEM.