Table 2. Antimicrobial susceptibility of pks-positive and pks-negative Klebsiella pneumoniae isolates.
| Antimicrobial agenta | N (%) of pks-positive isolates (n = 67) | N (%) of pks-negative isolates (n = 333) | p | ||
|---|---|---|---|---|---|
| Resistantb | Susceptible | Resistantb | Susceptible | ||
| Amikacin | 0 | 67 (100.0) | 25 (7.5) | 306 (91.9) | 0.013 |
| Aztreonam | 0 | 67 (100.0) | 68 (20.4) | 260 (78.1) | <0.001 |
| Ceftazidime | 0 | 67 (100.0) | 68 (20.4) | 245 (73.6) | <0.001 |
| Cefazolin | 4 (6.0) | 63 (94.0) | 109 (32.7) | 221 (66.4) | <0.001 |
| Ciprofloxacin | 0 | 67 (100.0) | 92 (27.6) | 232 (69.7) | <0.001 |
| Cefepime | 0 | 66 (98.5) | 40 (12.0) | 283 (85.0) | 0.005 |
| Cefoxitin | 3 (4.5) | 63 (94.0) | 82 (24.6) | 236 (70.9) | <0.001 |
| Cefuroxime | 5 (7.5) | 62 (92.5) | 104 (31.2) | 221 (66.4) | <0.001 |
| Cefotaxime | 1 (1.5) | 66 (98.5) | 58 (17.4) | 259 (77.8) | <0.001 |
| Ertapenem | 0 | 67 (100.0) | 8 (2.4) | 324 (97.3) | 0.36 |
| Gentamicin | 0 | 67 (100.0) | 84 (25.2) | 239 (71.8) | <0.001 |
| Piperacillin/Tazobactam | 0 | 67 (100.0) | 61 (18.3) | 256 (76.9) | <0.001 |
| Ticarcillin/Clavulanate | 2 (3.0) | 62 (92. 5) | 100 (30.0) | 215 (64.6) | <0.001 |
| Trimethoprim/Sulfamethoxazole | 1 (1.5) | 66 (98.5) | 120 (36.0) | 213 (64.0) | <0.001 |
aAmpicillin was also tested but not included in analysis because isolates of K. pneumoniae have intrinsic resistance to this agent. bResistant data do not include intermediate results.