Table 3. Factors associated with carriage of pks gene cluster in Klebsiella pneumoniae clinical isolates.
| Variable (n) | No. (%) of isolates | Pa | ORb | 95%CIb | Pb | |
|---|---|---|---|---|---|---|
| pks-Positive | pks-Negative | |||||
| Total (400) | 67 | 333 | ||||
| Age | 0.719 | |||||
| < = 15 y.o. (18) | 2 (3.0) | 16 (4.8) | 0.749 | |||
| 16–64 y.o. (163) | 26 (38.8) | 137 (41.1) | 0.723 | |||
| > = 65 y.o. (219) | 39 (58.2) | 180 (54.1) | 0.533 | |||
| Specimen source | 0.014 | |||||
| Blood (100) | 17 (25.4) | 83 (24.9) | 0.938 | 2.525 | 0.644–9.902 | 0.184 |
| Respiratory (100) | 26 (38.8) | 74 (22.2) | 0.004 | 1.501 | 0.387–5.828 | 0.557 |
| Urine (100) | 9 (13.4) | 91 (27.3) | 0.017 | Reference | ||
| Abscess & Others (100) | 15 (22.4) | 85 (25.5) | 0.588 | 0.809 | 0.203–3.222 | 0.763 |
| Capsular type | <0.001 | |||||
| K1 (33) | 26 (38.8) | 7 (2.1) | <0.001 | 1112.7 | 103.535–11957 | <0.001 |
| K2 (45) | 19 (28.4) | 26 (7.8) | <0.001 | 187.456 | 19.813–1773.6 | <0.001 |
| K20 (23) | 11 (16.4) | 12 (3.6) | <0.001 | 425.418 | 38.925–4649.5 | <0.001 |
| K57 (8) | 1 (1.5) | 7 (2.1) | 1 | 25.798 | 1.16–573.73 | 0.04 |
| K62 (25) | 9 (13.4) | 16 (4.8) | 0.022 | 508.24 | 42.06–6141.5 | <0.001 |
| Non-K1, K2, K20, K57, K62 (266) | 1 (1.5) | 265 (79.6) | <0.001 | Reference | ||
| Antimicrobial resistance | <0.001 | |||||
| Resistant to <= 1 agent (272) | 65 (97.0) | 207 (62.2) | 18.281 | 3.288–101.658 | 0.001 | |
| Resistant to >= 2 agents (128) | 2 (3.0) | 126 (37.8) | Reference | |||
aP value by univariate analysis. Only variables having statistical significance by univariate analysis were subject to multivariate analysis. bP value by multivariate analysis; OR, odds ratio; CI, confidence interval.