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. 2017 Feb 23;10:8. doi: 10.1186/s13072-017-0115-7

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — SMYD5 and H4K20me3 occupy repetitive DNA elements in ES cells. Comparison of H4K20me3, H3K9me3, and SMYD5 enriched sequences and annotated repetitive sequences (http://www.repeatmasker.org). Empirical cumulative distribution (ECDF) for the percent coverage of a a LINE or LTR repeat class or b family member (L1 or ERVK) across all H4K20me3 (top) or H3K9me3 (middle) islands, or SMYD5 regions (bottom) relative to random genomic regions (black). Y-axis shows the percentage of genes that exhibit a percent repeat length less than the value specified by the x-axis. A line shifted to the right means a systematic increase in the percent coverage of a repeat element in ChIP-Seq peaks relative to random genomic sequences. p value for all <2.2e−16 (Kolmogorov–Smirnov test)