Table 3.2.
Comparison of oxygenation dynamics parameter after iloprost inhalation between patients with a positive and negative response to acute vasoreactivity testing in the chronic thromboembolic pulmonary hypertension group
| Factors | Negative group (n = 150) | Positive group (n = 25) | ||||||
|---|---|---|---|---|---|---|---|---|
| Before AVT | After AVT | Statistics | P | Before AVT | After AVT | t | P | |
| SaO2 (%) | 91.55 (5.03) | 89.85 (5.12)* | −5.392† | <0.001 | 91.54 ± 3.58 | 88.60 ± 4.58* | 3.406 | 0.002 |
| SvO2 (%) | 62.90 (14.50) | 65.50 (13.55)* | −4.996† | <0.001 | 68.16 ± 8.06 | 66.67 ± 8.08 | 1.131 | 0.269 |
| PaO2 (mmHg) | 62.70 (14.03) | 56.65 (12.65)* | −6.178† | <0.001 | 61.98 ± 12.74 | 55.23 ± 11.17* | 4.367 | <0.010 |
| PvO2 (mmHg) | 35.80 (9.80) | 35.50 (7.25) | −0.037† | 0.971 | 44.46 ± 9.70 | 40.94 ± 9.44* | 2.119 | 0.045 |
| Qs/Qt (%) | 23.68 ± 10.00 | 29.31 ± 11.97* | −5.818‡ | <0.001 | 25.72 ± 8.98 | 30.85 ± 16.61 | −1.538 | 0.146 |
Data are presented as mean ± SD or median (interquartile range). *Means the data after AVT versus that before AVT, P<0.05; †Z value; ‡t value. The paired-sample t-test was used to analyze the date of normal distribution. The Wilcoxon signed-rank test of two related samples was used to analyze the date of nonnormal distribution. AVT: Acute vasoreactivity testing; PaO2: Partial pressure of oxygen in arterial blood; PvO2: Mixed venous oxygen partial pressure; Qs/Qt: Intrapulmonary shunt; SaO2: Arterial oxygen saturation; SvO2: Mixed venous oxygen saturation; SD: Standard deviation. 1 mmHg = 0.133 kPa.