Supplementary Table 2.
Comparison of hemodynamics and oxygenation dynamics parameters before and after acute vasoreactivity testing in patients with pulmonary arterial hypertension
| Factors | Before AVT (n = 80) | After AVT (n = 80) | Statistics | P |
|---|---|---|---|---|
| mPAP (mmHg) | 55.96 ± 17.51 | 48.07 ± 17.81* | 8.052† | <0.001 |
| mBP (mmHg) | 89.73 ± 12.18 | 83.88 ± 14.91* | 4.354† | <0.001 |
| PVR (dyn·s−1·m−5) | 1105.50 (1031.25) | 896.50 (801.50)* | −6.585‡ | <0.001 |
| SVR (dyn·s−1·m−5) | 2088.00 (1139.00) | 1815.00 (1011.00)* | −5.379‡ | <0.001 |
| CO (L/min) | 3.44 ± 1.55 | 3.73 ± 1.52* | −4.091† | <0.001 |
| SaO2 (%) | 94.50 (3.70) | 93.85 (4.72)* | −2.390‡ | 0.017 |
| SvO2 (%) | 66.20 ± 10.34 | 69.53 ± 9.44* | −3.578† | 0.001 |
| PaO2 (mmHg) | 75.69 ± 18.05 | 70.58 ± 16.53* | 3.456† | 0.001 |
| PvO2 (mmHg) | 39.30 (7.80) | 38.40 (8.60) | −0.638‡ | 0.524 |
| Qs/Qt (%) | 17.70 (13.13) | 28.85 (17.65)* | −3.775‡ | <0.001 |
Data are presented as mean ± SD or median (interquartile range). *Means the data after AVT versus that before AVT, P<0.05; †t value; ‡Z value. The paired-sample t-test was used to analyze the date of normal distribution. The Wilcoxon signed-rank test of two related samples was used to analyze the date of nonnormal distribution. AVT: Acute vasoreactivity testing; CO: Cardiac output; mBP: Mean blood pressure; mPAP: Mean pulmonary arterial pressure; PaO2: Partial pressure of oxygen in arterial blood; PvO2: Mixed venous oxygen partial pressure; PVR: Pulmonary vascular resistance; Qs/Qt: Intrapulmonary shunt; SaO2: Arterial oxygen saturation; SvO2: Mixed venous oxygen saturation; SVR: Systemic vascular resistance; SD: Standard deviation. 1 mmHg = 0.133 kPa.