Table 4.
Comparison of hemodynamics and oxygenation dynamics parameters after acute vasoreactivity testing inpatients with CTEPH and PAH
| Factors | CTEPH (n = 175) | PAH (n = 80) | Statistics | P |
|---|---|---|---|---|
| ΔmBP (mmHg) | −4.00 (7.00) | −4.00 (9.00) | −0.860* | 0.390 |
| ΔmPAP (mmHg) | −5.00 (7.00) | −7.00 (8.75) | −1.224* | 0.221 |
| ΔPVR (dyn·s−1·m−5) | −233.00 (226.50) | −212.50 (319.00) | −0.094* | 0.925 |
| ΔSVR (dyn·s−1·m−5) | −309.00 (537.50) | −292.00 (516.00) | −0.253* | 0.801 |
| ΔCO (L/min) | 0.39 ± 0.65 | 0.28 ± 0.62 | 1.239† | 0.217 |
| ΔPaO2 (mmHg) | −5.00 (10.50) | −5.25 (12.88) | −0.145* | 0.885 |
| ΔPvO2 (mmHg) | 0 (5.08) | −0.20 (5.90) | −0.085* | 0.932 |
| ΔQs/Qt (%) | 5.57 ± 10.07 | 6.18 ± 11.68 | −0.360† | 0.719 |
Data are presented as mean ± SD or median (interquartile range). “Δ”: The change in the index after iloprost inhalation. *Z value; †t value. The independent-sample t-test was used to analyze the date of normal distribution. The rank sum test of two independent samples (Mann-Whitney U-test) was used to analyze the date of nonnormal distribution. CTEPH: Chronic thromboembolic pulmonary hypertension; PAH: Pulmonary arterial hypertension; AVT: Acute vasoreactivity testing; CO: Cardiac output; mBP: Mean blood pressure; mPAP: Mean pulmonary arterial pressure; PaO2: Partial pressure of oxygen in arterial blood; PvO2: Mixed venous oxygen partial pressure; PVR: Pulmonary vascular resistance; Qs/Qt: Intrapulmonary shunt; SaO2: Arterial oxygen saturation; SvO2: Mixed venous oxygen saturation; SVR: Systemic vascular resistance; SD: Standard deviation. 1 mmHg = 0.133 kPa.