Concatenated sequences of the cps genes of serogroup 6 isolates. (A) Polymorphic nucleotide sites within the concatenated wciP, wzy, and wzx genes are displayed as in Fig. 3. The cps profile corresponding to each sequence is shown. The first block of sequences are from serotype 6A isolates, and all of the sequences including and below the 3-1-1 profile are from serotype 6B isolates. The last block shows the divergent class 2 sequences. One serotype 6A sequence (cps profile 7-7-6) and one serotype 6B sequence (cps profile 8-7-5) are perfect mosaics between class 1 and class 2 sequences. (B) The polymorphic amino acids in the translated concatenated sequences are shown. The dashes in the cps profile 9-10-1 in panels A and B represent deleted nucleotides or amino acids. (C) Neighbor-joining tree constructed from the concatenated nucleotide sequences; taxa are labeled according to their cps profiles. ▴, serotype 6A isolates; ▪, serotype 6B isolates with class 1 sequences; •, serotype 6B isolates with class 2 sequences; ▵, serotype 6B isolates APH-10 and AAU-19 (cps profile 3-1-1); ○, serotype 6B isolates APO-445 and APO-446 (cps profile 8-7-5); ∅, serotype 6A isolate ACH-C2 (cps profile 7-7-6).