Table 2.

Associations between hepcidin and participant characteristics and iron indices

Variable	Regression Coefficient	95% CI	P	β coefficienta
Univariate linear regression for log10(hepcidin)
Age (years)	0.048	0.025, 0.070	<0.001	0.090
Sexb	−0.24	−0.30, −0.18	<0.001	−0.16
Hb (g/dL)	0.13	0.11, 0.15	<0.001	0.30
log10(ferritin)	0.37	0.34, 0.40	<0.001	0.46
log10(sTfR)	−0.50	−0.58, −0.43	<0.001	−0.27
log10(sTfR‐F)	−0.52	−0.56, −0.47	<0.001	−0.43
log10(CRP)	0.15	0.12, 0.18	<0.001	0.23
β‐thalassemia trait	−0.02	−0.16, 0.12	0.76	−0.006
HbE trait	0.15	−0.12, 0.43	0.27	0.023
α‐thalassemia trait	0.12	0.044, 0.19	0.002	0.066
α‐homozygous or compound heterozygous thalassemia	0.49	0.16, 0.81	0.003	0.063
Multiple linear regression model for log10(hepcidin)
Log10(ferritin)	0.27	0.24, 0.30	<0.001	0.34
Log10(sTfR)	−0.25	−0.32, −0.17	<0.001	−0.13
Hb (g/dL)	0.05	0.04, 0.07	<0.001	0.13
Log10(CRP)	0.10	0.07, 0.12	<0.001	0.15

All variables were included in the multiple regression analysis. Only variables with P < 0.05 were included in the final fitted model.

^aVariables standardized to have a variance of 1, allowing comparison of regression coefficients between variables.

^bCoded variable: Male = 0; Female = 1.