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Toll‐like receptor 4 (TLR4)‐mediated reduction in glomerular filtration rate. Selection of proposed mechanisms by which TLR4 activation contributes to reduced glomerular filtration in S‐AKI (for details see text). LPS (Lipopolysaccharide); TLR4 (Toll‐like receptor 4); TGF (Tubuloglomerular feedback).
