Table 1.
Child‐Pugh Classification System
| Points Scored for Observed Findings | |||
|---|---|---|---|
| Clinical and Biochemical Measurementsa | 1 | 2 | 3 |
| Hepatic encephalopathy (grade)b | None (Grade 0) | 1 or 2 | 3 or 4c |
| Ascites | Absent | Slight | Moderated |
| Serum bilirubin (mg/dL) | <2.0 | 2.0–3.0 | >3.0 |
| Serum albumin (g/dL) | >3.5 | 2.8–3.5 | <2.8 |
| Prothrombin timee | |||
| Seconds prolonged | <4 | 4–6 | >6 |
| International Normalized Ratio (INR) | <1.7 | 1.7–2.3 | >2.3 |
a
Child‐Pugh class based upon sum of points: class A, 5–6 points; class B, 7‐9 points; class C, 10‐15 points.
b
Grades 0 through 4 based on signs, symptoms, and tests.
c
Stage 3 and 4 encephalopathy were excluded. However, those subjects who received medication to prevent recurrent encephalopathy were scored based on the degree of encephalopathy off treatment.
d
Moderate or controlled by diuretics.
e
If a discrepancy between seconds prolonged and INR, points scored for INR were used.