Table 1.

Peptide therapeutics on the market

Trade name	Peptide	Company	Molecular properties	Related reference
Copaxone	Glatiramer	Teva	Four amino acids (l‐glutamic acid, l‐alanine, l‐lysine and l‐tyrosine) in a defined molar ratio	105, 106
Lupron	Leuprolide	Abbott	Synthetic nonapeptide analogue of naturally occurring gonadotropin‐releasing hormone (GnRH or LH‐RH)	107, 108
Vicoza	Liraglutide	Novo	97% homologous to native human GLP‐1 (7–37) by substituting arginine for lysine at position 34 and addition of a fatty acid chain	109
Zoladex	Goserelin	AZ	Natural LHRH/GnRH decapeptide with two substitutions to inhibit rapid degradation.	110, 111
Sandostatin	Octreotide	Novartis	Longer acting synthetic octapeptide analogue of naturally occurring somatostatin	112, 113
Forteo	Teriparatide	Lilly/Amylin	Recombinant form of parathyroid hormone consisting of the first (N‐terminus) 34 amino acids, which is the bioactive portion of the hormone	114, 115
Byetta	Exenatide	Lilly/Amylin	Synthetic version of exendin‐4, a hormone found in the saliva of the Gila monster	116, 117
Cubicin	Daptomycin	Cubist	Cyclic lipopeptide, consisting of 13 amino acids, 10 of which are arranged in a cyclic fashion and three on an exocyclic tail	118, 119
Integrilin	Eptifibatide	Merck	Cyclic heptapeptide composed with S–S bridge, two unnatural building blocks and amide	120, 121
Angiomax/angiox	Bivalirudin	Medicines	20‐amino acid polypeptide	122, 123
Fortical	Calcitonin	Upsher‐Smith	32‐amino acid polypeptide	124, 125, 126
Somatuline	Lanreotide	Ipsen	Cyclic peptide that is a long‐acting analogue of somatostatin.	127, 128