Table. Characteristics of blaNDM-7–producing Enterobacteriacae isolates from patients in a military hospital, Gabon, 2016*.
Characteristic | Isolate |
|||
---|---|---|---|---|
S1 | S2 | S3 | S4 | |
Species | Klebsiella pneumoniae | K. pneumoniae | K. pneumoniae | Enterbacter cloacae |
No. contigs | 83 | 104 | 86 | 61 |
Genome and plasmid size, bp |
5′688′′217 |
5′710′′179 |
5′699′′938 |
4′860′′761 |
Resistome genes according to antibiotic class | ||||
β-lactams | ||||
blaSHV-28 | + | + | + | |
blaCTX-M-15 | + | + | + | |
blaNDM-7 | + | + | + | + |
blaOXA-9 | + | + | + | |
act-17 | + | |||
ampR | + | |||
lap-2 | + | |||
blaSHV-12 | + | |||
blaTEM-104 | + | |||
Aminoglycosides | ||||
aac6′-Ib | + | + | + | |
aac3-IIa | + | + | + | |
ant3 | + | + | + | |
aac3 | + | |||
Sulfamids | ||||
folA | + | + | + | + |
sul1 | + | + | + | |
sul2 | + | + | + | + |
dhfr1 | + | + | + | + |
Others | ||||
fosA | + | + | + | |
arr-ms | + | + | + | |
tetD | + | + | + | |
tetA-2 | + | |||
qnrS1 | + | |||
mphA | + | |||
cat | + |
*aac3, aminoglycoside 3-N-acetyltransferase; aac3-IIa, aminoglycoside N-acetyltransferase AAC(3)-IIa; aac6′-lb-cr, AAC(6′)-Ib-cr family aminoglycoside N(6′)-acetyltransferase; aac6′-Ib, AAC(6′)-Ib family aminoglycoside 6′-N-acetyltransferase; act-7, cephalosporin-hydrolyzing class C β-lactamase ACT-17; ampR, ampicillin chromosomal-mediated β-lactamase; ant3, streptomycin 3′′-adenylyltransferase; arr-ms, rifampin ADP-ribosyl transferase; blaCTX-M-15, class A extended-spectrum β-lactamase CTX-M-15; blaNDM-7, New Delhi metallo-β-lactamase NDM-7; blaOXA-9, oxacillin-hydrolyzing class D β-lactamase OXA-9; blaSHV-12, β-lactamase SHV-12 ; blaSHV-28, class A β-lactamase SHV-28; blaTEM-104, β-lactamase TEM-104; cat, chloramphenicol acetyltransferase; dhfr1, dihydrofolate reductase type 1; folA, dihydrofolate reductase; fosA, fosfomycin resistance glutathione transferase FosA; lap-2, class A β-lactamase LAP-2; qnrS1, quinolone resistance pentapeptide repeat protein QnrS1; mphA, Mph(A) family macrolide 2′-phosphotransferase; sul1, sulfonamide-resistant dihydropteroate synthase Sul1; sul2, sulfonamide-resistant dihydropteroate synthase Sul2; tetA-2, tetracycline resistance protein, class C; tetD, tetracycline efflux MFS transporter Tet(D).