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NAMPT and POU5F1 differentially regulate p-MTOR via AKT-independent p-PTEN signaling. (A) WB analysis was performed on NAMPT KD or (B) POU5F1 KD cells for p-MAPK1/3 (Tyr208), MAPK3, p-AKT (Ser473) and AKT protein levels. WB analysis was performed for (C) FK866-treated, (D) NAMPT KD or (E) POU5F1 KD cells for p-MTOR (Ser2448). WB analysis was performed for (F) NAMPT KD or (G) POU5F1 KD cells for p-PTEN (Ser380).
