Table 4.
Linear regression analysis | Dependent variable: Carotid intima-media thickness | |||||
---|---|---|---|---|---|---|
Independent variables | *P | Beta (Standardized) | Beta±SE (Unstandardized coefficients) | †P | Beta (Standardized) | Beta±SE (Unstandardized coefficients) |
Age, years | <0.001 | 0.476 | 0.010±0.001 | <0.001 | 0.406 | 0.008±0.001 |
Gender, male | <0.001 | 0.429 | 0.155±0.027 | <0.001 | 0.244 | 0.085±0.016 |
Family history of CAD | 0.136 | 0.096 | 0.035±0.023 | |||
HDL-C, mg/dL | 0.323 | 0.070 | 0.001±0.001 | |||
LDL, mg/dL | 0.009 | 0.161 | 0.001±0.000 | |||
LDL/HDL ratio | 0.294 | 0.068 | 0.012±0.011 | |||
TK/HDL ratio | 0.691 | 0.026 | 0.003±0.008 | |||
EAT, mm | <0.001 | 0.323 | 0.028±0.005 | <0.001 | 0.450 | 0.031±0.003 |
Constant | 0.125 | -0.132±0.086 | 0.737 | 0.191±0.045 | ||
Adjusted R2 | 0.571 | 0.534 | ||||
Logistic regression analysis | Dependent variable: Presence of carotid plaque | |||||
Independent variables | *P | Wald | OR (95% CI) | †P | Wald | OR (95% CI) |
Age, years | 0.075 | 3.2 | 1.073 (0.993–1.159) | |||
Gender, male | 0.066 | 3.4 | 6.147 (0.890–42.5) | |||
Family history of CAD | 0.141 | 2.2 | 2.791 (0.711–10.9) | |||
HDL-C, mg/dL | 0.491 | 0.5 | 1.024 (0.958–1.094) | |||
LDL, mg/dL | 0.002 | 9.1 | 1.034 (1.012–1.057) | 0.020 | 5.4 | 1.013 (1.002–1.023) |
LDL/HDL ratio | 0.068 | 3.3 | 1.699 (0.963–2.988) | |||
TK/HDL ratio | 0.111 | 2.5 | 1.396 (0.926–2.104) | |||
EAT, mm | 0.002 | 9.7 | 1.634 (1.199–2.226) | <0.001 | 20.4 | 1.386 (1.203–1.597) |
Constant | <0.001 | 18.5 | <0.001 | 31 | ||
Adjusted R2 | 0.455 | 0.203 |
CAD - coronary artery disease; EAT - epicardial adipose tissue thickness; HDL - high density lipoprotein; LDL - low density lipoprotein; SE - standard error. Linear and logistic regression analyses with enter method were used for all relevant independent variables that were included if they were significantly different in the univariate analyses*. In addition, the analysis was repeated after a pre-elimination with stepwise method for the independent variables†