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. 2016 Jun 29;16(12):900–915. doi: 10.14744/AnatolJCardiol.2016.6755

Table 5.

AMP derivation based on pre and/or in-hospital medication use: “all patients, by index event final diagnosis”

STEMI (n=514) UA/NSTEMI (n=520)
Antiplatelets, n (%)
 None 0 (0.0) 0 (0.0)
 ASA only 7 (1.4) 48 (9.2)
 Clopidogrel only 0 (0.0) 4 (0.8)
 ASA + Clopidogrel 404 (78.6) 436 (83.8)
 ASA + GP IIb/IIIa 2 (0.4) 1 (0.2)
 Clopidogrel + GP IIb/IIIa 1 (0.2) 0 (0.0)
 ASA + Clopidogrel + GP IIb/IIIa 100 (19.5) 31 (6.0)
By thrombolytic therapy
YES 68 (13.2) 0 (0.0)
 None 0 (0.0) 0 (0.0)
 ASA + Clopidogrel 67 (98.5) 0 (0.0)
 ASA + GP IIb/IIIa 0 (0.0) 0 (0.0)
 Clopidogrel + GP IIb/IIIa 0 (0.0) 0 (0.0)
 ASA + Clopidogrel + GP IIb/IIIa 1 (1.5) 0 (0.0)
NO 446 (86.8) 520 (100.0)
 None 0 (0.0) 0 (0.0)
 ASA only 7 (1.6) 48 (9.2)
 Clopidogrel only 0 (0.0) 4 (0.8)
 ASA + Clopidogrel 337 (75.6) 436 (83.8)
 ASA + GP IIb/IIIa 2 (0.4) 1 (0.2)
 Clopidogrel + GP IIb/IIIa 1 (0.2) 0 (0.0)
 ASA + Clopidogrel + GP IIb/IIIa 99 (22.2) 31 (6.0)
By anticoagulant therapy
YES 482 (93.8) 422 (81.2)
 None 0 (0.0) 0 (0.0)
 ASA only 6 (1.2) 24 (5.7)
 Clopidogrel only 0 (0.0) 3 (0.7)
 GP IIb/IIIa only 0 (0.0) 0 (0.0)
 ASA + Clopidogrel 373 (77.4) 366 (86.7)
 ASA + GP IIb/IIIa 2 (0.4) 1 (0.2)
 Clopidogrel + GP IIb/IIIa 1 (0.2) 0 (0.0)
 ASA + Clopidogrel + GP IIb/IIIa 100 (20.7) 28 (6.6)
NO 32 (6.2) 98 (18.8)
 None 0 (0.0) 0 (0.0)
 ASA only 1 (3.1) 24 (24.5)
 Clopidogrel only 0 (0.0) 1 (1.0)
 ASA + Clopidogrel 31 (96.9) 70 (71.4)
 ASA + Clopidogrel + GP IIb/IIIa 0 (0.0) 3 (3.1)
Number of antiplatelet medications
 Total 0 0 (0.0) 0 (0.0)
1 7 (1.4) 52 (10.0)
2 402 (78.2) 437 (84.0)
3 105 (20.4) 31 (6.0)
4 0 (0.0) 0 (0.0)
By anticoagulant use
 Unfractioned heparin YES 270 (52.5) 193 (37.1)
0 0 (0.0) 0 (0.0)
1 3 (1.1) 8 (4.1)
2 195 (72.2) 171 (88.6)
3 72 (26.7) 14 (7.3)
4 0 (0.0) 0 (0.0)
Low molecular weight heparinx YES 318 (61.9) 284 (54.6)
0 0 (0.0) 0 (0.0)
1 4 (1.3) 20 (7.0)
2 249 (78.3) 242 (85.2)
3 65 (20.4) 22 (7.7)

ASA - acetylsalicylic acid; GP IIb/IIIa - Glycoprotein IIb/IIIa inhibitors; NSTEMI - non- ST-segment elevation myocardial infarction; STEMI - ST-segment elevation myocardial infarction; UA-unstable angina. Table presents use of any loading or maintenance dose of listed medications pre- or in-hospital

did not take ASA, clopidogrel or a GP IIb/IIIa Inhibitor; may have received prasugrel or ticlopidine; *Time to treatment calculated as; #hours from symptom onset to first in-hospital administration of any of the associated medications, where data available missing dates/times of pre-and in-hospital medications replaced with the imputed date/time of hospital admission. Note-for patients with no in-hospital antiplatelet use recorded, any discharge antiplatelet is assumed to have also been used in-hospital