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. 2016 Jun 29;16(12):923–930. doi: 10.14744/AnatolJCardiol.2016.6780

Table 3.

Effects of V. album on heart rate, left ventricular volume, and function in heart failure rats (mean±S.D.)

Parameters Measurement time Control, n=10 ISO, n=8 VA, n=8 P*
Heart rate 14th day 318±16 358±15c 353±10c <0.0001
Final day 315±9 358±15c 337±9c,d <0.0001
P# =0.2640 =0.9650 =0.0020
LVEDV 14th day 203.8±19.5 232.0±11.7a 228.5±22.1 =0.0060
Final day 203.7±17.0 253.8±30.0a 232.0±7.9b <0.0001
P# =0.9730 =0.0380 =0.6960
LVESV 14th day 53.8±9.7 69.0±1.9a 68.5±5.4a <0.0001
Final day 54.2±6.3 109.3±11.6c 80.8±4.1c,e <0.0001
P# =0.8430 <0.0001 <0.0001
LVFS 14th day 42.4±3.3 40.5±1.2 40.9±2.1 =0.2280
Final day 43.3±2.9 30.6±1.8c 36.6±1.2c,e <0.0001
P# =0.0650 <0.0001 <0.0001
LVEF 14th day 72.6±3.7 70.2±1.1 69.8±3.9 =0.1590
Final day 73.3±3.1 56.7±2.6c 65.2±1.5c,e <0.0001
P# =0.1120 <0.0001 =0.0140

ISO - isoproterenol group; LVEDV - left ventricular end-diastolic volume; LVEF - left ventricular ejection fraction; LVESV - left ventricular end-systolic volume; LVFS - left ventricular fractional shortening; VA - V. album treatment group.

*

P was calculated using one-way ANOVA;

#

P was calculated using paired sample t-test;

a

Posthoc: P<0.01 vs. control group;

b

Posthoc: P<0.001 vs. control group;

c

Posthoc: P<0.000 vs. control group;

d

Posthoc: P<0.05 vs. isoproterenol group;

e

Posthoc: P<0.000 vs. isoproterenol group