Table 2.
Baseline demographic and clinical parameters of the study population
| Parameters | Tertile 1 SS <23 (n=131) |
Tertile 2 SS 23–32 (n=79) |
Tertile 3 SS >32 (n=42) |
P (T 1-2) |
P (T 1–3) |
P (T 2-3) |
|---|---|---|---|---|---|---|
| Age, years | 59.2±12.0 | 60.6±12.0 | 66.9±9.6 | 0.656 | 0.001 | 0.015 |
| Sex: female, n % | 41 (31) | 18 (23) | 5 (12) | 0.351 | 0.032 | 0.386 |
| DM, n % | 51 (39) | 37 (47) | 24 (57) | 0.503 | 0.098 | 0.521 |
| Hypertension, n % | 73 (56) | 43 (54) | 31(74) | 0.981 | 0.097 | 0.099 |
| Hyperlipidemia, n % | 53(41) | 46 (58) | 28 (67) | 0.031 | 0.008 | 0.641 |
| Family history, n % | 13 (10) | 29 (37) | 14 (33) | <0.001 | 0.003 | 0.897 |
| Smoking, n % | 40 (31) | 45 (57) | 25 (60) | <0.001 | 0.002 | 0.958 |
| Previous history, n % | ||||||
| MI | 23 (18) | 26 (33) | 20 (48) | 0.036 | <0.001 | 0.180 |
| PCI | 8 (21) | 21 (27) | 19 (45) | 0.550 | 0.021 | 0.199 |
| Previous medication, n % | ||||||
| Platelet inhibitors | 23 (17) | 34 (43) | 21 (50) | <0.001 | <0.001 | 0.689 |
| Beta-blockers | 45 (34) | 33 (42) | 18 (43) | 0.534 | 0.587 | 0.993 |
| ACE inhibitors/ARBs | 83 (63) | 50 (63) | 25 (60) | 0.998 | 0.897 | 0.913 |
| Statins | 65 (50) | 38 (48) | 17 (41) | 0.975 | 0.560 | 0.706 |
| Stroke/TIA, n % | 0 (0) | 3 (4) | 7 (17) | 0.330 | <0.001 | 0.001 |
| PAD, n % | 3 (2) | 19 (24) | 17 (41) | <0.001 | <0.001 | 0.027 |
| LVEF, % | 52.5±7.8 | 43.9±8.1 | 42.3±8.1 | <0.001 | <0.001 | 0.527 |
| Glucose, mg/dL | 143.3±80.7 | 157.3±76.8 | 160.0±93.2 | 0.449 | 0.479 | 0.983 |
| Creatinine, mg/dL | 0.9±0.3 | 1.0±0.9 | 1.4±1.1 | 0.440 | <0.001 | 0.014 |
| LDL, mg/dL | 111.1±34.5 | 112.3±43.0 | 115.7±39.2 | 0.973 | 0.778 | 0.889 |
| HDL, mg/dL | 39.1±18.2 | 37.6±10.3 | 40.6±13.3 | 0.773 | 0.844 | 0.562 |
| TG, mg/dL | 177.1±108.4 | 156.0±95.1 | 134.2±82.7 | 0.306 | 0.044 | 0.493 |
| GRACE score | 133.4±45.9 | 167.7±63.6 | 204.1±69.1 | <0.001 | <0.001 | 0.002 |
| TIMI score | 2.21±1.32 | 3.46±1.41 | 4.31±1.54 | <0.001 | <0.001 | 0.004 |
| CHA2DS2-VASc-HS score | 2.89±1.31 | 4.19±1.60 | 5.55±2.28 | <0.001 | <0.001 | <0.001 |
Data are expressed as mean±SD and/or median (minimum–maximum) or count (percentage) for categorical variables
ACE - angiotensin converting enzyme; ARB - angiotensin receptor blockers; DM - diabetes mellitus; HDL - high-density lipoprotein; LDL - low-density lipoprotein; LVEF - left ventricular ejection fraction; MI - myocardial infarction; PAD - peripheral arterial disease; PCI - percutaneous coronary intervention; T - tertile; TG - triglycerides