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. Author manuscript; available in PMC: 2018 Feb 1.
Published in final edited form as: Circ Heart Fail. 2017 Feb;10(2):e003658. doi: 10.1161/CIRCHEARTFAILURE.116.003658

Figure 3. Inhibition of endogenous H-Ras attenuates hypertrophy and exacerbates pressure overload-induced cardiac dysfunction.

Figure 3

A. Left ventricular weight/tibia length (LVW/TL) was determined in TAC and sham operated groups. B. Cardiomyocyte cross-sectional area was determined by wheat germ agglutinin (WGA) staining. C. Representative WGA images. D. Fibrosis was determined by Masson’s Trichrome staining. E. Representative images shown. Scale bar, 100 μm. F. Extent of apoptosis was determined by TUNEL staining. G. Echocardiographic analysis was performed to determine left ventricular ejection fraction (%LVEF). N=4–11 per group. Data are mean ± SEM. *,P<0.05.